double take season one

The new england journal of medicine
film production & story development

In 2022, Youtube announced they were partnering with the world’s most influential medical publisher, The New England Journal of Medicine (NEJM), to create a video series that would bring trusted health information to both medical audiences and non-medical audiences. The series, which NEJM named the Double Take series, explores culturally relevant and evidence-based health information in videos that are engaging, accessible and free to online viewers. 

We were brought on by NEJM as their main external partner on the project. For season one, we created video stories on 5 topics— Sickle Cell Disease, Migraine, Weight and Health, Atrial Fibrillation, and Malaria. Through interviews with medical experts and patients, we dove deep into these topics and crafted video stories built for YouTube’s diverse audiences. 

With the goal of reaching both physicians and patients, most topics include at least two videos designed for the distinct needs of these audiences. We further segmented the information into 60 second trailers for social media, with the goal of directing viewers to the longer videos hosted on YouTube and The New England Journal of Medicine website. 

Trinity Love sits at the table with her family.
Play Video about Trinity Love sits at the table with her family.

sickle cell & gene therapy

Sickle Cell disease has received a lot of media attention due to recent, exciting gene therapy advancements that could have implications for other diseases as well.

These advancements include gene editing, where the patient’s cells are taken from their body ‘fixed’ and put back into their body. Some have even gone as far as calling it a cure for sickle cell. In the words of one of the interviewees, “the science is as elegant as it gets.” 

However, these advances include significant risk, cost, possible infertility, and often aren’t accessible to the majority of the patient population. Moreover, because of structural and systemic racism, many of the individuals living with sickle cell disease are currently not getting the basic level of care that they need. 

As one interviewee put it, “Sickle cell disease is the canary in the coal mine of health equity.”

In this video, we aimed to balance these messages—explaining and celebrating the recent scientific advances and advocating for the social and health justice gains that will make needed care accessible and equitable. 

Video is a medium uniquely capable of communicating with nuance and holding space for multiple perspectives. 

In our story design and research, we seek a range of perspectives and strive to look at multiple sides of an issue, following the lead of those who are the most impacted, in this case that was people living with sickle cell disease. Featuring multiple voices can bring depth and complexity to a topic and also makes the final video more engaging. 

our client

The New England Journal of Medicine

our role

Story Design
Film Production
Editing

Our team

Story Contributors:
Trinity Love
Terry Jackson
Phillip Okwo
Teonna Woolford, Cassandra Trimnell
Alexis Thompson
Matthew Heeney
Michael Debaun
Melesa Love

Directors and Producers: Catherine Orr
Elena Rue

Consulting Producer:
Cassandra Trimnell

Cinematographer:
Cheryl Hess
Brynmore Williams
Nikki Bramley
Leo Maco

Editors:
Catherine Orr
Katie Falkenberg
Elena Rue

Assistant Editor:
Andie Rea

Motion Graphics Artist:
Victoria Blair

Colorist:
Patrice Bowman

Cassandra Trimnell, founder of Sickle Cell 101, plays with her daughter at home.
Alexis Thompson, MD, MPH, has a conversation with a patient about Sickle Cell disease and gene therapy.
Michael Debaun, MD, MPH, sits with patient and family, answering their questions about sickle cell disease and gene therapy.
Scientist working on gene therapy in lab.
Dr. Elizabeth Loder talks about migraine disease
Play Video about Dr. Elizabeth Loder talks about migraine disease

changing our understanding of migraine disease

For decades and perhaps even centuries, migraines have been considered a disorder of “nervous women.” Today, migraines are considered among the top causes of disability and the critical need for managing the disease is being taken much more seriously. 

Recent medical advances have made this chronic condition less debilitating for many, but continued progress in the field is essential. 

Early in our partnership with the New England Journal of Medicine, we uncovered their goal of creating videos that reached both physicians and patients—two distinctly different audiences with vastly different experiences and starting points.

That’s why, for this topic and many others in this series, we created two videos —a ‘physician-facing’ version and a ‘patient-facing’ version. 

Both versions aim to inform and inspire, but the health information is curated and communicated differently depending on who the content is intended to serve. 

In this ‘physician-facing version’, we explored information that would support clinicians caring for patients with this common condition. Acute and preventative treatments are discussed, as well as barriers to care that must be overcome so more patients can access needed therapies. 

In the ‘patient perspective’ video, we aimed to show the journey of individuals living with this debilitating disease and the ways research is changing the perception of migraines. Watch it here.

our client

The New England Journal of Medicine

our role

Story Design
Film Production
Editing

Our team

Story Contributors:
Cynthia Armand
Elizabeth Loder

Directors and Producers:
Catherine Orr
Elena Rue

Cinematographers:
Artina Michelle Nimpson
Nikki Bramley
Jonathan Marzolla
Arthur Thompson

Audio Engineers:
John Osborne
Helian Zhang

Editors:
Catherine Orr
Elena Rue

Assistant Editors:
Rachel Dennis Bolanos
Andie Rea

Motion Graphics Artists:
Victoria Blair
Andie Rea

Colorist:
Patrice Bowman

Dr. Cynthia Armand explains the pathophysiology of migraines
Patient with severe migraine attack lies in bed in dark room.
Migraine patient waiting on exam table.
Migraine patient holds head in pain.
Dr. Sriram Machineni listens to a patient in documentary about how weight impacts health
Play Video about Dr. Sriram Machineni listens to a patient in documentary about how weight impacts health

when weight impacts health

In 2013, the American Medical Association recognized obesity as a disease, however many of the current cultural narratives around weight continue to perpetuate harmful bias and stigma.

In these video stories, we explored the evidence— dispelling the myth that weight is entirely determined through willful control. Medical experts describe the way weight is influenced by hormones and genetics and discuss treatment options including bariatric surgery and drug therapies.  

Our goal with this project was to communicate the current research and understanding of obesity and combat harmful narratives that surround the disease. 

To shift the audience’s perspective, we relied on archival footage of news and talk shows to present the overwhelming cultural messaging around weight. We then negated these narratives with medical experts describing the science behind weight, such as weight-regulating pathways and the body’s defended fat mass set point. 

We created four videos, one patient-focused as well as a three-part series covering pathophysiology, bariatric surgery and medications, and supporting patients. 

our client

The New England Journal of Medicine

our role

Story Design
Film Production
Editing

Our team

Story Contributor:
Louis Aronne
Sarah Bramblette
Ania Jasterboff
Sriram Machineni
Nikki Massie

Directors and Producers:
Elena Rue
Catherine Orr

Cinematographer:
Vanessa Carr
Kyle Kelley

Jason Arthurs
Molly Brock
Caleb Childers

Editors:
Elena Rue
Catherine Orr

Assistant Editor:
Andie Rea

Motion Graphics Artists:
Victoria Blair
Andie Rea


Colorist:
Patrice Bowman

Dr. Ania Jasterboff speaks with a patient in documentary about how weight impacts health
scale and measurement instruments in doctor's exam room
Hand picking up bunch of bananas in store
Dr. Louis Aronne, profile in office.
Dr. William Sauer explains what atrial fibrillation is in a short documentary about AFib and ablation procedures
Play Video about Dr. William Sauer explains what atrial fibrillation is in a short documentary about AFib and ablation procedures

what is atrial fibrillation?

Atrial fibrillation is a common yet complex medical condition affecting the heart’s electrical system. The result is irregular and often very rapid heart beats. While AFib is complex, modern medicine has made the condition manageable and treatable. 

For patients and non-specialist, AFib and its treatments can be intimidatingly technical to understand and communicate. Our goal was to break down AFib clearly and efficiently while engaging viewers by showing how far medical knowledge has advanced. 

Our story design process involved looking for clear explanations of AFib diagnosis and treatment. Through our research and interviews, we uncovered a historical perspective that allowed us to contrast current medical knowledge with the less sophisticated treatment and uncertainties of the past.

Historical context is an effective storytelling strategy for many scientific topics. By showing what was once mysterious and unknown, viewers are engaged in a narrative arc of progress and discovery. 

In this video for patients and families, viewers see how far we’ve come in our understanding of AFib and learn about the various treatment options, including antiarrhythmic medications and the procedure of catheter ablation. 

We also created an instructional video for doctors that has received well over a hundred thousand views. Commenters describe the video as “very clear and insightful,” “plain, matter of fact wording,” and an “excellent video explanation.” 

our client

The New England Journal of Medicine

our role

Story Design
Film Production
Editing

Our team

Story Contributor:
Elliott Antman
Jane Leopold
Williams Sauer
Paul Zei

Directors and Producers:
Elena Rue
Catherine Orr

Cinematographer:
Nikki Bramley
Dave Lovering

Editors:
Mimi Schiffman
Elena Rue
Catherine Orr

Assistant Editor:
Andie Rea

Motion Graphics Artists:
Victoria Blair
Steph Khoury
Andie Rea


Colorist:
Patrice Bowman

A stat about risk of stroke
Dr. Elliott Antman in a short documentary about atrial fibrillation.
Dr. Jane Leopold in a short documentary about atrial fibrillation.
Image of heart after an ablation procedure
Malaria - Drug Resistance Treatment Drug Administration: Photo Credit Saw HTEE K Paung for Shoklo Malaria Research Unit
Play Video about Malaria - Drug Resistance Treatment Drug Administration: Photo Credit Saw HTEE K Paung for Shoklo Malaria Research Unit

Can we eliminate malaria?

Beginning in the year 2000 and for around 15 years, Malaria deaths rates plunged. A global focus, scaled up control efforts, and new evidence and research all lead to a lower disease burden and fewer deaths. Headlines promised science was leading us toward a “Malaria-free world.” But then in 2016, progress stopped.  

This was the compelling story we learned as we spoke with leaders and experts on the topic of Malaria. Our background in journalism uniquely equips us to discover and dive into stories embedded in research. Unanswered questions drive us through the creation process and often provide a narrative structure that hooks and engages viewers.  

Part of our training as journalists is gathering information from sources with different perspectives and points of view. This ensures our stories are well-rounded and accurate. We often aim to speak with people directly involved or impacted by a topic, which yields more credible and rich accounts. For this topic we spoke with non-U.S. experts representing different areas of research, most of whom are living and working in areas most affected by Malaria.

We recorded these interviews virtually, incorporating key quotes and insights into the final video. We also integrated the larger themes from these interviews into a single voice-over narration written to communicate the story concisely and cohesively.  

Footage and images were sourced from others doing research globally. This video includes videos and photos from the Global Fund to Fight AIDS, Tuberculosis, and Malaria; MMV Medicines for Malaria Venture; Caz Tanner; Suphak Nosten for Shoklo Malaria Research Unit; and Saw HTEE K Paung for Shoklo Malaria Research Unit.

our client

The New England Journal of Medicine

our role

Story Design
Film Production
Editing

Our team

Story Contributor:
Flaminia Catteruccia
Abdoulaye Diabaté
Cristina Donini
François Nosten
Scott O'Neill
Faith Osier
Aung Pyea Phyo
Nicholas White

Directors and Producers:
Elena Rue
Catherine Orr

Assistant Producer:
Andie Rea

Writers:
Catherine Orr
Andie Rea

Editors:
Catherine Orr
Elena Rue

Assistant Editor:
Andie Rea

Voiceover Artist:
Tendai Dongo

Motion Graphics Artists:
Victoria Blair
Andie Rea

Scientists studying mosquito modification for malaria eradication - Credit: The Global Fund to Fight AIDS, Tuberculosis, and Malaria
Malaria microscope slide
Modified Mosquitoes in malaria research laboratory - Credit: The-Global-Fund-to-Fight-AIDS,-Tuberculosis-and-Malaria-progressive.
Scientists studying drug resistant malaria - Credit: Caz Tanner